NEXT GENERATION SEQUENCING (NGS) FACILITY

Union Minister of Science and Technology inaugurated the Next Generation Sequencing (NSG) facility at the Centre for Cellular and Molecular Biology (CCMB) in Hyderabad. This NGS facility is the fourth such facility in the country.

• Genome sequencing is figuring out the order of DNA nucleotides, or bases, in a genome—the order of As, Cs, Gs, and Ts that make up an organism’s DNA.

Image Credits:http://www.0425.info/ngs-template-preparation-8d44b4c3ef5d4d4ef8d2cd.html

• Next Generation Sequencing (NGS) allows parallel Genome sequencing, resulting in the generation of Giga bases of data in a short amount of time.
• Benefits: This has reduced the cost per genome significantly, making genomic data more accessible to individual researchers. Decreasing costs are making genomics an attractive and integral part of any successful bioscience research project.
• Application: The NSG would help prenatal genetic screening and counselling, thereby generating large scale genomic data critical for diagnosis and therapy. It would be of help, especially to patients suffering from rare genetic disorders.
• Recent development: The recent NSG facility at the CCMB in Hyderabad can sequence 18,000 samples in 8 minutes. With this, the CCMB can now sequence up to 30 human genomes or 384 diagnostic samples in a day.

Source: PIB